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For the coprimary endpoints of systemic vascular resistance index and renal blood flow, a sample size of 12 subjects per group would have 85% power to detect a 10% reduction in systemic vascular resistance index and a 15% increase in renal blood flow in response to apelin compared to placebo with a two-sided 5% significance level 7,8

What is the focus of the 4X Blend formulation

Lee EK, Gorospe M: Minireview: Posttranscriptional regulation of the insulin and insulin-like growth factor systems

Jeschke MG, Barrow RE, Herndon DN: Insulinlike growth factor I plus insulinlike growth factor binding protein 3 attenuates the proinflammatory acute phase response in severely burned children