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Description

This report is current as of the date of the literature search specified in the Research Methods section

Treatment frequency varies based on individual goals

Evidence: What does the current research actually support, and how preliminary is it

This axis hinges on the cAMP nucleotide-metabolizing membrane-ectoenzyme phosphodiesterase (PDE) and CD73 (41) and it may flank or synergize the known ATP/NAD + -catabolic pathways