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DOI: Received: Accepted: Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-87225-0 Online ISBN: 978-3-030-87225-0 eBook Packages: Living Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences Keywords Tobacco Nicotine Harm reduction Biomarkers of exposure (BoE) Biomarkers of potential harm (BoPH) Electronic nicotine delivery systems (ENDS) Tobacco heating products (THP) Smokeless tobacco Snus Switching Potentially reduced exposure products (PREP) Potentially reduced risk products (PRRP) Oxidative stress Inflammation

In France, according to a survey[4] from Inserm and Inca[5], since the introduction of plain packaging in 2017, fewer young people have experimented with tobacco: 1 in 5 young people aged 12 to 17 (20.8%) experimented with tobacco for the first time in 2017 compared to 1 in 4 (26.3%) in 2016

LEVIN: And so he's like, all right, well, that didn't work