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Moreover, GHRP-2 can significantly enhance the analgesic efficacy of morphine, and this potentiation occurs via a mechanism that does not appear to require ghrelin receptor signaling

Potential mechanisms by which peptide exposure could influence surgical outcomes include dysregulated angiogenesis contributing to hematoma formation, altered inflammatory signaling affecting early wound healing, and perturbations in collagen organization that may influence soft-tissue integrity during the critical postoperative period