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japonicum (in rabbits) fail to elicit strong antibody mediated responses, Sm 16, long considered a possible vaccine candidate, does not merit investigation as such (101, 105)

By introducing known triggers of ECD into these 3D models, it would be possible to observe not only how ECs are directly affected, but also how their interactions with surrounding cell types are altered within the complex microenvironment of the spheroids

It should only be taken by people enrolled in an authorised clinical trial, under the supervision of a qualified clinician