ghk cu peptide dosing recommendations GHK-Cu Dosage: Clinical Guidance for Safe Administration – PlexusDx Peptide Dosage Calculator — Free

Grivennikov, S

(2015), BioMed Research International 2015:648108, PubMed 26236730 Statistics from research literature Discovered by Loren Pickart in human blood plasma in 1973 , as a factor extending the longevity of cultured liver cells The smallest peptide with documented pharmacological activity: 3 amino acids (Gly-His-Lys) + one Cu ion Molecular weight: 402 Da EU cosmetic INCI name: Copper Tripeptide-1 (registered in EU Commission CosIng database) Gene expression modulation: 4 000 human genes (Connectivity Map dataset, Pickart 2015) Plasma level in healthy humans declines from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 (62 % decrease) Most-studied bioactivities: fibroblast proliferation , type I/III collagen synthesis , antioxidant activity (SOD upregulation) Reference sources (PubMed) Pickart L., Vasquez-Soltero JM., Margolina A

[DOI] [PubMed] [Google Scholar] 13.Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z et al

Though conventional wisdom and anecdotal evidence says that this property is helpful for dark under-eye circles and puffy eyes , we have to mention that the double-blind research we have found about a 3% caffeine gel concluded that " the overall efficacy of the selected caffeine gel in reducing puffy eyes was not significantly different from that of its gel base ." But you know, the proof is in the pudding