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Alba M, Fintini D, Sagazio A, et al

Cigarette smoke-induced pulmonary emphysema in scid-mice

Must be used as a single-dose preparation

Br J Clin Pharmacol 2025 demonstrates that co-infusing a GLP-1 agonist with glucagon produces a perfectly additive HR response (+4 bpm + +4 bpm = +7 bpm at 60 min in n=12 lean males), confirming that glucagon drives chronotropy via a parallel pathway independent of GLP-1R cross-reactivity