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Clinical findings in severe patients with COVID-19 infection are in consistent with the above mention literature

Duvallet C, Gibbons SM, Gurry T, Irizarry RA, Alm EJ

Lactate as a G Protein-Coupled Receptor Agonist Hydroxycarboxylic acid receptor 2 (HCA2) is a GPCR also known as PUMA-G (upregulated protein in macrophages by IFN-) (143), HM74A, and GPR109A (144)