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Preclinical studies have investigated AHK-Cus role in fibroblast activity, wound contraction models, and the regulation of matrix metalloproteinases (MMPs) enzymes central to tissue remodelling research

The role of kynurenine and its metabolites in comorbid chronic pain and depression

This is because the absence of aralar does not exclude mitochondrial glutamate synthesis, especially if a substantial amount of -ketoglutarate is supplied from non-glucose source in these young animals

Arch Biochem Biophys 95:483493 Loewus MW, Bedgar DL, Saito K, Loewus FA (1990) Conversion of Lsorbosone to l-ascorbic acid by a NADP dependent dehydrogenase in bean and spinach leaf