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Description

British Journal of Haematology 129, (6) (Jun): 755-62

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This action is bacteriostatic rather than bactericidal, meaning bacterial growth is prevented rather than organisms being directly destroyed

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Mechanistic Research Perspective Disruption of FOXO4p53 protein interaction Activation of p53-mediated apoptosis pathways Modeling senescent cell survival and removal mechanisms Analysis of transcription-factor signaling networks Investigation of age-related cellular stress responses Primary Research Applications Cellular Senescence Studies: FOXO4-DRI is widely used in experimental models to investigate how senescent cells accumulate and influence tissue function

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High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma

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