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The role of DNA methylation and histone modifications in the pathogenesis of hematological malignancies and solid cancers: mechanisms, clinical implications, and therapeutic potential

Gene targeting by the TAL effector PthXo2 reveals cryptic resistance gene for bacterial blight of rice

Furthermore, the redox system not only involves redox-associated enzymes, such as the glutathione biosynthesis pathway, GPXs, GR, catalase, superoxide dismutase (SOD), and NOXs, but also intertwines with glucose metabolism, fatty acid oxidation, and mitochondrial function for the generation of reducing equivalent NADPH, with glutamine metabolism for the supplement of glutamate for glutathione synthesis, and with other signaling pathways including NRF2-mediated upregulation of the antioxidant system for a better adaptation to oxidative stress