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For adults, experts recommend a combined daily intake of 1,100 to 1,600 mg of omega-3 fatty acids

In animal studies, AOD-9604 reduced body weight gain by over 50% in obese mice during a 19-day treatment period, and significantly increased fat oxidation all without affecting insulin sensitivity or glucose regulation.[1,3] A randomized controlled trial in humans found that participants taking 1 mg of AOD-9604 daily lost an average of 2.8 kg (~6 lbs) over 23 weeks, compared to 0.8 kg (~1.7 lbs) in the placebo group

In vitamin B12 deficiency, there is an over-production of both serotonin and dopamine and so one would expect that the number of receptors that can respond to stimulus is gradually reduced

Immunology 153 , 179189 (2018)