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The experimental protocol was designed as follows: When the tumor volume reached ~100 mm, the tumor-bearing mice were Five groups ( n = 6 per group) receiving PBS control, Psa-AR, enzalutamide monotherapy, pimitespib monotherapy, or enzalutamidepimitespib combination therapy were randomly assigned

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cerevisiae led to the discovery of Cu chaperones that guide Cu into selected cuproproteins (Robinson & Winge, 2010)