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Taken together, these data indicated a direct correlation between lipid peroxidation and neurodegeneration, with the oxidized phospholipids suggestive of ferroptosis

Mechanistically, PSAT1 possesses the distinctive capacity to perpetually generate -KG in the absence of glutamine

[DOI] [PubMed] [Google Scholar] 150.Jenkins T.G., Aston K.I., James E.R., Carrell D.T

Arch Biochem Biophys 433:166175 Banerjee R, Zou CG (2005) Redox regulation and reaction mechanism of human cystathionine-beta-synthase: a PLP-dependent hemesensor protein