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Minor adjustments in breathing are usually sufficient to adjust the pH of the blood by changing how much CO 2 is exhaled

Lancet 2021 Phase 2 (monotherapy) Lau et al., n=706, 26 weeks

In a study of 10 healthy male volunteers, omeprazole, in doses of 20 mg-40 mg per day, caused a significant decrease in the oral absorption of methylcobalamin, vitamin B12