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Considering the paramount importance of oxLDL in the pathogenesis of atherosclerosis, it is reasonable to evaluate the role of antioxidants in the treatment of the disease as adjuvant strategies to lipid-lowering or anti-inflammatory therapies designed to reduce the risk of cardiovascular disease (230)

Apixaban concentration was determined via a validated liquid chromatography with tandem mass spectrometry method with a dynamic range of 1.00200 ng/mL using 100 L of human serum:buffer performed at Alta Analytical Laboratory Inc