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Clinical Research Findings In a controlled study using a collagenase-induced osteoarthritis rabbit model, researchers administered weekly intra-articular injections of 0.25 mg AOD-9604 for 4-7 weeks

This association suggests that bacterial infections, as evidenced by antibiotic use, may contribute to manic episodes through immune activation, highlighting infection prevention and treatment as potential targets

Results Biochemical characterization of human FHOD3 We purified the C-terminal half of human FHOD3L (FHOD3L-CT), encompassing the FH1 domain, FH2 domain, and C-terminal tail, which is typically sufficient for actin assembly in vitro and in vivo (Figure 1, Figure 1figure supplement 1) (Courtemanche, 2018