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Name: dihexa human clinical trials status 2026 5MG Research Material Clinical Research in 2026:What's Changing
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Nat Commun 16 , 3389 (2025)

Hypoxia also induces cellular adaptations which can hinder the efficacy of chemotherapy, such as reduced cellular uptake of drugs due to increased cellular acidity and drug efflux pump expression [82], whilst some chemotherapeutic agents require oxygen in order to facilitate their cytotoxicity [24]