Treatment strategies may include pain medication, using a spinal brace for support, physical therapy, electronic stimulation of nerves (transcutaneous electrical nerve stimulation), adjusting nerve signals (neuromodulation), injections of anti-inflammatory steroids into the spine (epidural steroid injection), inserting a small device between the spine bones (interspinous spacer), and surgical procedures to relieve pressure on the spinal cord (surgical decompression)
In 1993, Sikiric and colleagues in Zagreb isolated a cytoprotective protein from human gastric juice, called Body Protection Compound (BPC), whose fragment 157 (15 amino acids) reproduces most of its regenerative activity
There are many scaffold proteins that are associated along with c-MET receptor and leads to activation of downstream signal transduction pathways that include mitogen-activated protein kinase (MAPK) cascades, extracellular signal-regulated kinase 1 (ERK1) and ERK2, Jun amino-terminal kinases (JNKs) and p38, the phosphoinositide 3-kinaseAkt (PI3KAKT) axis, signal transducer and activator of transcription proteins (STATs), and the nuclear factor-b inhibitor- (ib)nuclear factor-b (NF-b) complex [33]
(2017) 67:974989.e6
