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Integration of hiPSC technology with small-molecule high-throughput screening (HTS) facilitates the identification of novel pharmacotherapeutic agents, whereas transcriptomic profiling enables comprehensive gene expression analysis of patient-specific organoids

[5] Lall S, Tung LY, Ohlsson C, Jansson JO, Dickson SL

10.1038/cdd.2013.138 212

These data suggest that ghrelin may aid in two ways: (1) by amplifying the remaining dopaminergic signaling through the D1R-GHSR1a dimer, and (2) by providing neuroprotective effects that may aid in slowing the progression of further dopaminergic degeneration, which may be the result of GHSR signaling alone