glutathione peroxidase upregulation brain cholesterol

glutathione peroxidase upregulation brain cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage Glutathione peroxidase 4‐dependent glutathione high‐consumption

Name: glutathione peroxidase upregulation brain cholesterol metabolism: physiological versus pathological aspects in intracerebral hemorrhage Glutathione peroxidase 4‐dependent glutathione high‐consumption
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Glutathione peroxidase 4dependent glutathione highconsumption drives acquired platinum chemoresistance in lung cancerderived brain metastasis Liu 2021 Clinical and Translational Medicine Wiley Online Library GPX4 independent ferroptosisa new strategy in disease's therapy Cell Death Discovery 13 reasons why the brain is susceptible to oxidative stress PMC The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity: Cell Reports

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Scaricamazza et al., 2020)

Common metabolic pathways involved in ferroptosis, such as (seleno) thiol metabolism, mitochondrial respiration iron handling, mevalonate pathway, and fatty acid metabolism, directly impact cellular sensitivity to lipid peroxidation and ferroptosis