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Since the very beginning, Roberts stomach cytoprotection/adaptive cytoprotection/organoprotection has been in the focus on the demonstration of the particular beneficial effect of the cytoprotectants, using prostaglandins as the prototype, but also other standard cytoprotectants

The mobile phase was composed of solvent A (10 mM ammonium acetate and 0.2% formic acid in water) and solvent B (10 mM ammonium acetate and 0.2% formic acid in 90% ACN)

Each of these molecules exerts distinct effects on cellular function, both locally and distally, through individual molecular targets [12, 13]

Dialysis is a prohibited method under M1.1, as blood is taken out from the patient and filtered, before being reintroduced back into the patients circulatory system