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Description

Clin Microbiol Rev 2015;28:23764

10.3390/CANCERS15092436 15 BuczyskaA.SidorkiewiczI.KociuszkoM.AdamskaA.SiewkoK.DzicioJ.et al (2023a)

Cells were cultured in DMEM/F-12 medium (#11320-033, Gibco) + 10%FBS (#10091148, Gibco) + P/S antibiotics (Gibco) supplemented with EGF (10ng/uL, BD Bioscience), Y-27632 dihydrochloride (10uM, Tocris), R-spondin 1 (250 ng/mL, R&D Systems), B27 (1x, #12587010, Invitrogen) and Normocin (ant-nr-1, InvivoGen)

Being a sole IgG1 Fc fragment, efgartigimod is the only FcRn antagonist in the current clinical pipeline that does not harbor selected V regions specific for FcRn