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PLoS One 8(4):e60921

Therefore, for SLE and LN treatment, adoptive transfer of Tregs can be directly applied, either as polyclonal Tregs or as engineered variants with a receptor of high affinity for the target autoantigen, such as TCR-Tregs or CAR-Tregs, to eliminate or deactivate aberrant immune cells and reduce inflammation in AIDs (75)

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Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease