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PRP is a concentrated solution of platelets derived from the patients own blood

[,] Owing to acute liver failure, chronic hepatitis, or cirrhosis, the clearance of ammonia by the liver is diminished, they may reach to the brain, the elevated levels of ammonia and an inflammatory response work in synergy to cause astrocytes to swell and fluid to accumulate in the brain (cerebral edema), thus, affect cerebral function [,] [Figure 7]

These cases indicate that secondary parkinsonism may occur atypically, with rapid development of symptoms against the background of significant alcohol intoxication [8]