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Women with endometriosis may have gastrointestinal symptoms such as bloating, IBS, constipation, and nausea

The metabolic reprogramming is executed by activation of several transcription factors, such as HIF, HK2, lactate dehydrogenase 5 (LDH5), lactate dehydrogenase A (LDHA), PDK1, PI3K, Akt, mTOR, EGFR, etc., which induce the Warburg effect, suppress oxidative metabolism in mitochondria, limit pyruvate entry into the tricarboxylic acid (TCA) cycle, trigger anabolism, and endorse lactate formation

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Springer, Singapore, pp 2940 Naveed M, Mitter B, Reichenauer TG, Wieczorek K, Sessitsch A (2014) Increased drought stress resilience of maize through endophytic colonization by Burkholderia phytofirmans PsJN and Enterobacter sp