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Houghton SC, Eliassen AH, Zhang SM, Selhub J, Rosner BA, Willett WC, et al

The attending physician attributed the death to pre-existing coronary disease rather than the study drug

However, future prospective studies and randomised trials using an agreed set of harmonised measures and blood biomarkers are needed to fully ascertain the utility of vitamin B 12 in relation to the prevention or delay in the onset of depression in older adults