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A study Withdrawal syndrome caused by naltrexone in opioid abusers by Hassanian-Moghaddam et al., involving 132 patients reported that 96.2% experienced agitation, 38.6% had altered levels of consciousness, 28% experienced nausea, 27.3% had vomiting, 24.2% reported abdominal pain, 16.7% experienced diarrhea, 15.9% had bone and muscle pain, 12.9% experienced tachycardia, and 11.4% had dilated pupils

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