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Pain medications vs peptides Traditional pain meds (NSAIDs, opioids): Block pain signals to brain Reduce inflammation temporarily Mask pain without healing Side effects (stomach damage, addiction, kidney issues) Stop working when you stop taking them Peptides for pain: Heal damaged tissue causing pain Reduce inflammation at source Promote tissue repair and regeneration Minimal side effects Results can be permanent (tissue healed) Key difference: Medications manage symptoms

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The American Academy of Neurology and International Restless Legs Syndrome Study Group (IRLSSG) have published evidence-based and best practice guidelines for the long-term treatment of restless legs syndrome/Willis-Ekbom disease