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3.2.3 Phenotypic flexibility Phenotypic flexibility is a component of phenotypic plasticity, but involves rapid, reversible within-individual variation

A similar conclusion was given by Van Cutsem et al

Common signs of B12 deficiency include: Persistent fatigue that doesnt improve with rest Difficulty concentrating or brain fog Mood changes, including low mood or irritability Tingling or numbness in the hands and feet Weakness or shortness of breath with normal activity Pale skin or a smooth, swollen tongue B12 deficiency can develop silently for months before symptoms become noticeable, which is why its frequently missed

This present study not only revealed the expression changes of vasoactive intestinal peptide [and its] receptors within human nucleus pulposus tissue, but also demonstrated [its] protective effects [against] degeneration, said Jingchuan Sun, professor in the Department of Orthopedic Surgery in Changzheng Hospital, and co-lead author of the study