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Numbness limited to the hand No neck pain Symptoms worse at night Positive wrist compression tests Symptoms improve when shaking the hand Neck stiffness or pain Pain radiating from shoulder into arm Weakness above the elbow Symptoms triggered by neck movement Shoulder blade discomfort Sometimes both conditions can occur simultaneously

Melioidosis often presents with long periods of latency before disease becomes clinically apparent, with reactivated bacterial proliferation occurring when cellular immunity is suppressed (hence the high degree of co-occurrence of active melioidosis and diabetes previously discussed)

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It has been shown that a lethal dose of DCVC in mice leads to inhibition of cell division, inhibition of renal repair, and acute renal failure (Korrapati et al., 2005, Vaidya et al., 2003a, Vaidya et al., 2003b)