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For the 1-round group, there was an 8% decrease (not significant) in white blood cell count with one child initially having an elevated level, and all being normal at the end of the study

The overall disease control rate (defined as minimal response [MR] or better, or stable disease [SD] for 8 weeks) was 37.5% and, notably, was twofold higher in patients with a longer interval between the last daratumumab dose and isatuximab initiation (58.3% with 6-month washout after daratumumab vs

Adjusting vascular permeability, leukocyte infiltration, and microglial cell activation to rescue dopaminergic neurons in rodent models of Parkinsons disease

Wang C, Sun J, Liang Z, et al