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*Sexual (Steroid) Hormones *An increase in sexual (or steroid) hormones estrogen and testosterone has been linked to periods of increased bodily stress: they are highly active during teenage years for both males and females when the body is developing, and particularly in women during their menstrual cycles, pregnancy and menopause

On average, the vapor-produced scent dissipates much quicker than cigarette smoke

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Given that the gum had a relatively low C max and AUC compared with the NP, lozenge and published cigarette PK data, these results suggest that factors other than nicotine PK play an important role in overall likeability of a nicotine product