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Description

Live GFP images were blinded and the localization determined by two independent observers

Richie, professor of public health sciences and pharmacology and Ana Calcagnotto, research assistant in public health sciences

The solution was then placed in a 0.1 cm quartz cuvette and scanned using a CD spectrometer (J-815, JASCO Corporation, Japan) with the following parameters: scanning wavelength range of 185260 nm, scanning speed of 100 nm per min, bandwidth of 1.0 nm, response time of 0.50 s, and step resolution of 1.0 nm

Global alterations in DNA methylation have revealed a link between the transcriptional dysregulation of Bdnf and its promoter methylation, with Bdnf being a key factor downregulated in HD patients and various HD models