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Eur J Hum Genet 14 : 159166 Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB (2006) Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation

In addition, this effect may be enhanced in older adults, as they have a stronger and more diffuse oxygen consumption during cognitive effort (Rodrguez-Nieto et al., 2024)