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Policy Implementation and Enforcement Assessment of Underage Sales Violations in Tobacco Stores and Vape Shops, JAMA Pediatrics Data from the 2018 California Tobacco Control Programs Young Adult Tobacco Purchase Survey, which uses 18-19-year-olds as underage decoys to attempt to purchase either cigarettes or vape product, found that about half (49.8%) of tobacco and vape shops that primarily sell tobacco products did not check IDs for the youth, and 44.7% sold to them

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Furthermore, CSE led to the reduced pulmonary DCs and suppression of DC maturation in murine lymph nodes, accompanying with the decreased expression of MHC II and costimulatory molecules (CD80 and CD86) and an attenuated capacity of inducing T cell proliferation [112]