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Description

PMID: 24389430

These extracellular adhesion points are the most targetable TJ component for modulation of the paracellular barrier ( Within the intestinal tract, various claudin isoforms are expressed in a segment-specific manner, contributing to the unique barrier properties of selected regions

Cells were cultured and treated in a 37 C humidified incubator gassed with 5% CO 2 and 90% N 2 so as to achieve bone marrow level hypoxia of 5% O 2 or alternatively room air without N 2 to achieve 20% O 2