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Unlike many actives, azelaic acid is also considered safe during pregnancy a significant advantage for those navigating skin concerns while pregnant or breastfeeding, where options like retinoids and salicylic acid are off the table

Media were then aspirated and replaced with DMEM supplemented with 50 M DFO with or without 400 nM BafA or regular DMEM, and cells were incubated for an additional 24 h

The trace elements include several transition metals, but the actual set required for life varies

However, these models are important because they mimic pathology of NTG, including RGC loss, optic nerve atrophy, and visual impairment with normal IOP 2,3