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As an extracellular copper-dependent monoamine oxidase, Lysyl oxidase (LOX) catalyzes the crosslinking of collagen and elastin proteins into insoluble mature fibers to contribute tensile strength of collagen fiber and elasticity of elastin fiber 15,16,34,36,37,38

In gastrointestinal lesions (indomethacin (30 mg/kg s.c.), aspirin (400 mg/kg i.g.) and diclofenac (125 mg/kg i.p.)) studies, NaBPC157 (10 g or 10 ng/kg i.p.) was given regularly, either simultaneously and/or one hour prior to drug application (indomethacin)

Progresses in the field of drug design to combat tropical protozoan parasitic diseases

Cu(II) binding to this site is reversible, however, characterized by slow unassisted dissociation rate and picomolar affinity ( K D = 0.90 0.09 pM), determined with NTA or fast and His-assisted dissociation and apparent subpicomolar affinity ( K D = 34.7 4.5 fM)