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Nicotinic, glutamatergic and dopaminergic synaptic transmission and plasticity in the mesocorticolimbic system: Focus on nicotine effects ScienceDirect Explainer: The nico teen brain Nicotine addiction can become a cycle of dopamine release, withdrawal, and cravings that reinforces continued nicotine use. The tobacco industry profits from keeping this cycle going. What feels like relief is often Menthol facilitates dopamine releasing effect of nicotine in rat nucleus accumbens ScienceDirect
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