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Since insulin resistance appears to be associated with kidney stone risk (Assimos 2004

10.1016/j.heliyon.2024.e30983 190 XiongH.ZhouY.ZhouQ.HeD.DengX.SunQ.et al (2016)

Overall, changes of serum and urine metabolism in ESCC patients can reflect the characteristics of metabolic disorders in tumor tissues, emphasizing the potential utility of NMR-based biofluids metabolomics fingerprinting as a non-invasive predictor for ESCC detection

With that in mind, going back to kind of how the mitochondria fit into this, would you expect the mitochondria to be more likely to stay online and to be less easily shut down and less susceptible to being overwhelmed by oxidative stress and kind of go into that shutdown state if you have more mitochondria and the internal antioxidant system is built up