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This led to the development of PT-141, a version of Melanotan 2 tailored for sexual wellness, which reduces the tanning effects

Free Radic Biol Med (2025) 229:25163

They improve photoaging by modifying cellular differentiation programs by increasing epidermal proliferation and thickening, compacting the stratum corneum and improving the deposition of glycosaminoglycans in the stratum corneum and intercellular spaces of the epidermis (127)