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Herbal formulas (such as those listed in Table 1) are commonly used in in various academic centers in the West (such as the Memorial Sloan-Kettering Cancer Center [51], University of California, Los Angeles [52], University of California San Francisco [53], Cleveland Clinic [54], and Cornell University [55])

has served as a speaker, consultant and advisory board member for Schering-Plough, AbbVie, Merck Sharp & Dohme, UCB Pharma, Ferring, Cellerix, Takeda Pharmaceutical Company, Nycomed, Pharmacosmos, Actelion, Alpha Wasserman, Genentech, Grnenthal, Pfizer, AstraZeneca, Novo Nordisk, Cosmo Pharmaceuticals, Vifor, Johnson & Johnson and Nikkiso Europe GmbH

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Currently, three CRC phenotypes are related to the presence of MSI: MSI sporadic tumors, LS, and LLS (Figure 1)